Jiang Li

     Research Professor

     Email: lijiang80@shu.edu.cn

     Research interests: Nucleic acid biomimetic materials, nucleic acid molecular machines, and their theranostic applications in living cells.

Education

2003.9 – 2009.7: College of Life Sciences, Sichuan University, Genetics, Master's and Ph.D.

1999.9 – 2003.6: College of Life Sciences, Sichuan University, Biology, Bachelor's.

Work Experience

2023.6 – Present: Institute of Materials Biology, Shanghai University, Research Professor.

2018.10 – 2023.6: Shanghai Advanced Research Institute, Chinese Academy of Sciences, Research Professor.

2009.7 – 2018.10: Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Assistant/Associate Research Professor.

Representative Publications

1. Zhao, Y.; Cao, S.; Wang, Y.; Li, F.; Lin, L.; Guo, L.; Wang, F.; Chao, J.; Zuo, X.; Zhu, Y.; Wang, L.; Li, J.*; Fan, C.*, A temporally resolved DNA framework state machine 

   in living cells. Nat. Mach. Intell. 2023, 5, 980-990.

2. Wang, K.; Wei, Y.; Xie, X.; Li, Q.; Liu, X.; Wang, L.; Li, J.*; Wu, J.*; Fan, C., DNA-programmed stem cell niches via orthogonal extracellular vesicle-cell 

   communications.  Adv. Mater. 2023, 35, e2302323.

3. Chen, X.; Wang, Y.; Dai, X.; Ding, L.; Chen, J.; Yao, G.; Liu, X.; Luo, S.; Shi, J.; Wang, L.; Nechushtai, R.; Pikarsky, E.; Willner, I.; Fan, C.; Li, J.*, Single-stranded 

   DNA-encoded gold nanoparticle clusters as programmable enzyme equivalents. J. Am. Chem. Soc. 2022, 144, 6311-6320.

4. Guo, L.; Zhang, Y.; Wang, Y.; Xie, M.; Dai, J.; Qu, Z.; Zhou, M.; Cao, S.; Shi, J.; Wang, L.; Zuo, X.; Fan, C.; Li, J.*, Directing multivalent aptamer-receptor 

   binding on the cell surface with programmable atom-like nanoparticles. Angew. Chem. Int. Ed. 2022, 61, e202117168.

5. Huang, Q.; Chen, B.; Shen, J.; Liu, L.; Li, J.; Shi, J.; Li, Q.; Zuo, X.; Wang, L.; Fan, C.; Li, J.*, Encoding fluorescence anisotropic barcodes with DNA frameworks. 

   J. Am. Chem. Soc. 2021, 143, 10735-10742.

6. Li, J.*; Fan, C.*, A DNA nanodevice boosts tumour immunity. Nat. Nanotechnol. 2021, 16, 1306-1307.

7. Dey, S.; Fan, C.*; Gothelf, K. V.*; Li, J.*; Lin, C.*; Liu, L.; Liu, N.*; Nijenhuis, M. A. D.; Saccà, B.*; Simmel, F. C.*; Yan, H.*; Zhan, P., DNA origami. 

   Nat. Rev. Methods Primers 2021, 1, 13.

8. Chen, B.; Huang, Q.; Qu, Z.; Li, C.; Li, Q.; Shi, J.; Fan, C.; Wang, L.; Zuo, X.; Shen, J.*; Li, J.*, Probing transient DNA conformation changes with an intercalative 

   fluorescent excimer. Angew. Chem. Int. Ed. 2021, 60, 6624-6630.

9. Ge, Z.; Liu, J.; Guo, L.; Yao, G.; Li, Q.; Wang, L.; Li, J.*; Fan, C.*, Programming cell-cell communications with engineered cell origami clusters. 

   J. Am. Chem. Soc.  2020, 142, 8800-8808.

10. Jiao, K.; Zhu, B.; Guo, L.; Zhou, H.; Wang, F.; Zhang, X.; Shi, J.; Li, Q.; Wang, L.; Li, J.*; Fan, C.*, Programming switchable transcription of topologically 

   constrained DNA. J. Am. Chem. Soc. 2020, 142, 10739-10746.

（Updated by Mar. 5th  2025）